No serial comms - dead ESP32?

[tbar23]

I have a custom PCB with a pair of ESP32s and a PIC32 for USB/UART programming.
One of the ESP32s is working fine, but I see no serial communications on the second one. It shows up on my computer as a USB device, but I don't see any serial communication.
I have tried manual reset by grounding both the EN pin and IO0, but still no communication.

I suppose it is possible that the ESP32 is dead, but I'm wondering if there is anything else I can try before giving up on the hardware.

[ESP_Sprite]

Suggest you check your routing (can you show your schematic here?) and perhaps use a 'scope probe if the serial signals indeed end up at the correct ESP32 pins.