Hi @ESP_Sprite, you were right, that was the issue, changing to a different PIN works and now I can drive 2 motor too without any issue. Thanks for your help!

Hi all. I'm working on a simple project with a NEMA17 stepper motor driven by a TMC2208 driver connected to an ESP32. All is powered though a 12V 16A external power supply, directly to the stepper and through a LM-2596 (5V buck converter to the board). Here the schematic: stepper diagram.png Stepper...