My bad guys, i didnt know that a xtal was mandatory to run the chip, i didnt have it on my design if you could notice from the schematics. I have to redesign my board...
I have the esp32-s2 with the embedded 4mb rom and 2mb ram, is the external flash rom mandatory in this case?

Wierd, its pulling 6.7 mA constant and 3.1 mA when i pull EN LOW. And EN goes to 0 V when i pull it down.

Thank you for trying to help! No, i do not see anything on the monitor! Did you take a look at the power rails on the schematics? Do you think there is something wrong with it?
The power comes currently from the ESP-prog which i have read has an adequate power supply.

I have built a custom board with an ES32-S2 chip, I am trying to upload a test sketch to it using the UART and an FTD2204 adapter. It does seem to toggle the IO0 and EN correctly, but it seems it is timing out as folows: A fatal error occurred: Failed to connect to ESP32-S2: Timed out waiting for pa...